Introduction to the Seminar: ACARISIN™ / ECO-EFF™
SEMINAR: USE AND APPLICATION OF ACARISIN™ AND ECO-EFF™
Advanced Biotechnology Solutions for Food Protection
Welcome to this specialized seminar where we will explore the
Introduction to ACARISIN™ / ECO-EFF™
INTABIOTECH: A cutting-edge Biotechnology Research and Commercialization Company in Spain
Biotechnology at the Service of the Food Industry
ACARISIN™ and ECO-EFF™ are the result of years of advanced research in the laboratories of ND Pharma & Biotech and INTABIOTECH, representing a revolution in the approach to food safety.
These biotechnological food solutions have been specifically created and designed to address one of the most persistent challenges in the food industry: protection against mites, insects, and other contaminants that affect the quality and safety of stored food.
Unlike traditional chemical products, ACARISIN™ and ECO-EFF™ offer effective protection without compromising human health or the environment, aligning perfectly with current trends towards more natural and sustainable processes in food production.
"Our mission is to transform food protection through biotechnological solutions that guarantee safety without compromising health or the environment." - INTABIOTECH
Problem: Mites and Food Contamination
Main Threats
Mites and insects, such as molds and certain types of bacteria, pose a constant threat to a wide range of food products, especially:
  • Stored grains and cereals (wheat, rice, corn, barley, malt)
  • Ripened dairy products like aged cheeses
  • Fruits, vegetables, olives, pistachios, etc., pre and post-harvest.
  • Vegetable raw materials for the food industry
  • Animal feed and forage
Economic Impact
Infestations and their consequences lead to substantial economic losses:
  • Deterioration and direct contamination of the product
  • Significant reduction in shelf life
  • Rejection of entire batches in quality controls (Aflatoxins, Ochratoxins, Mycotoxins, etc.)
  • Damage to producer's reputation
  • Additional storage and treatment costs, and, if applicable, eventual destruction of food raw materials
Health Risks
Contamination by mites and their secondary damages carry serious health risks:
  • Production of mycotoxins and other toxic compounds
  • Allergenic potential for sensitive consumers
  • Disease transmission
  • Compromise of food safety
  • Non-compliance with sanitary standards
  • Loss and deterioration of reputation.
Currently, many industries rely on potentially harmful chemical treatments which, in addition to their inherent risks, face increasing regulatory restrictions and consumer rejection, creating an urgent need for effective and safe alternatives. (Eco-Phyto 2018 Initiative · Member State France).
Innovation: What is ACARISIN™?
Definition and Main Features
ACARISIN™ is an innovative food biotechnology solution specifically developed for the control and elimination of mites and insects in food products, with exceptional features:
Natural Origin: Formulated from naturally occurring mineral compounds, completely edible and safe for humans and animals
Triple Action: Acaricidal, insecticidal, and fungicidal properties in a single product, offering comprehensive protection, at low doses, and functioning as a technological processing aid or as food for phytosanitary use.
Food Safety: Complies with the strictest international food safety regulations. Its safe use is guaranteed by its ingredients belonging to the category of globally authorized Food Additives with no daily intake limit (ADI)-JECFA (FDA, FCC)
Sustainable Alternative: Effectively replaces traditional chemical pesticides without their associated harmful effects. It is above all a Food product.
ACARISIN™ represents a significant advance in food protection, combining efficacy with safety in a solution completely aligned with current demands for more natural products and sustainable processes in the food industry.
"ACARISIN™ is not simply a product; it is a philosophy of food protection that prioritizes human health and environmental respect without compromising effectiveness." - Principal Investigator, INTABIOTECH
Mechanism of Action
Direct Action
ACARISIN™ acts through direct contact with mites and insects, penetrating their exoskeleton and affecting their vital systems. The formulation, composed of ionic mineral salts and substances, alters the permeability of the cell membrane (or chitinous sheath in macroscopics) of the parasites, causing their rapid and effective elimination without generating resistance.
Destruction of Vital Substances
The product specifically attacks essential enzymes and proteins for mite survival, disrupting their fundamental metabolic processes. Thus, the physical-mechanical phenomenon produced is called "electroporation," which perforates the insect's chitinous sheath, preventing its repair and unbalancing the osmotic pressure equilibrium between the interior and exterior, making this difference incompatible with the organism's life. This selective action guarantees effectiveness against target organisms without affecting other elements of the environment or food quality, and without them being able to generate resistance to this effect.
Growth Inhibition
ACARISIN™ interferes with the reproductive cycles of mites and fungi, preventing the development of eggs and spores, and especially their hatching, particularly in grain spaces where other products may not be effective, such as in the case of rice. This inhibitory effect, or indirect biological control of the mite's life cycle, creates an unfavorable environment for the proliferation of new generations, significantly extending the period of protection.
Long-Term Prevention
The formulation creates a durable protective barrier that remains active for weeks or even months (depending on environmental conditions), effectively preventing re-infestations and providing continuous protection to stored products.
This is one of the main advantages of the product, or, in other words, as long as ACARISIN™ IS PRESENT - PROTECTION EXISTS.
This multilevel and sustained action distinguishes ACARISIN™ from conventional solutions, offering comprehensive protection that addresses not only current infestation but also its potential reappearance, ensuring product safety throughout its storage cycle.
Formulation and Safety
Innovative Composition
ACARISIN™ is formulated from a synergistic combination of food-grade and 100% natural-mineral salts and mineral substances, carefully selected and processed using advanced technology to maximize its effectiveness while preserving its innocuous nature:
  • Ionic salts and mineral substances with natural acaricidal properties
  • Their special identity and specific purity allow these substances to act on the metabolism of mites
  • Mineral substances present in nature that have a biological action that interrupts the reproductive cycles of parasites
  • Stabilizing elements that guarantee the persistence of the protective effect
  • 100% mineral components that leave no toxic residues
This unique composition has been developed after years of research, optimizing each component to ensure maximum efficacy with minimal impact.
Exceptional Safety Profile
The safety of ACARISIN™ has been rigorously verified through extensive toxicological and environmental studies:
  • Non-toxic to humans or domestic animals or industrial livestock
  • Total absence of harmful residues in treated foods
  • 100% natural mineral, with no environmental impact
  • No adverse effects on the organoleptic quality of food
  • Compatible with food processing and direct consumption
  • Complies with the most demanding international standards for products in contact with food (It is itself a Food).

Safety Certification: ACARISIN™ has undergone rigorous safety evaluations by independent laboratories, confirming its suitability for direct use in food intended for human consumption without the need for waiting periods or waiting to reuse facilities when used in this function.
Industrial Applications: Food and Value Chain
Cereal and Grain Protection
ACARISIN™ offers superior protection for all types of stored grains:
  • Wheat, rice, corn, oats, barley, and other cereals
  • Legumes and seeds for human consumption
  • Grains for flour production and derivatives
  • Seeds for planting and propagation
Its application prevents significant losses during prolonged storage and maintains nutritional quality intact.
Gourmet and Cured Products
Specialized protection for high-value-added products:
  • Cured cheeses during their ripening process
  • Facilities where all kinds of products are cured
  • Bakery and pastry products, flours, and processed foods
  • Gourmet foods susceptible to mites
ACARISIN™ protects these products and facilities without affecting or altering their organoleptic qualities or natural ripening processes.
Food Industry
Applications throughout the entire food value chain:
  • Protection of raw materials in industrial warehouses
  • Preventive treatment in production lines
  • Preservation of processed products
  • Protection during transport and distribution
Its versatility allows integration at multiple points in the production chain.
Livestock Sector
Solutions for the animal feed industry:
  • Protection of feed and forage
  • Treatment of livestock facilities
  • Prevention of cross-contamination
  • Improvement of the sanitary quality of animal feed
Contributes to animal health and, by extension, to food safety.
The versatility of ACARISIN™ allows its application in multiple industrial contexts, adapting to the specific needs of each sector and offering personalized solutions for each type of food product.
Industrial Applications: Other Sectors
Organic Agriculture
ACARISIN™ represents an ideal solution for the organic agriculture sector, where the absence of chemical residues is fundamental:
  • Treatment of certified organic crops
  • Post-harvest protection in organic agriculture
  • Storage of organic products
  • Pest prevention without compromising certifications
Its natural origin and absence of toxic residues make it the perfect ally for producers committed to sustainable agriculture.
Logistics and Transport
Protection during storage and transport is crucial to maintaining food quality and safety:
  • Preventive treatment of containers and silos
  • Protection during long-duration maritime transport
  • Conditioning of warehouses and logistics centers
  • Prevention of infestations at critical points in the supply chain
ACARISIN™ offers continuous protection even under variable temperature and humidity conditions.
Specialized Applications
The potential of ACARISIN™ extends beyond the food sector:
  • Protection of organic materials in museums and collections
  • Treatment of upholstery and textiles against dust mites
  • Applications in the pharmaceutical industry for raw materials of natural origin
  • Protection of cosmetic products with organic ingredients
Its versatility allows for specific adaptations to solve mite problems in very diverse contexts.

Adaptability: INTABIOTECH's R&D department offers formula adaptation services for the specific needs of each industry, optimizing its effectiveness for particular contexts.
ECO-EFF™: Ecological Efficiency Technology
"ECO-EFF™ represents the culmination of our development philosophy: maximum effectiveness with minimum environmental impact. It's not just about protecting food, but about protecting our planet."
A Step Forward in Sustainable Biosecurity
ECO-EFF™ is the natural evolution of ACARISIN™ technology, specifically developed to maximize ecological efficiency in demanding industrial environments:
Optimized Formulation: Enhances the protective effects of ACARISIN™ through a synergistic combination of additional ingredients, specially designed for complex industrial environments.
Industrial Sustainability: Developed specifically for large-scale processes, allowing the integration of biological protection into industrial production lines without significant modifications to existing protocols.
Chemical Reduction: Its implementation allows for a drastic reduction or complete elimination of chemical acaricides and insecticides in the food chain, contributing to the "green chemistry" strategy in the industry.
Complementarity: Can be used independently or as a complement to ACARISIN™ to enhance its effect in particularly demanding conditions or severe infestations.
ECO-EFF™ represents INTABIOTECH's response to the most demanding requirements of the modern food industry, where environmental sustainability must go hand in hand with effectiveness and economic viability.
Evidence and Usage Results
Empirical Data Supporting its Efficacy
Mite Control
Field studies show an 87-98% reduction in mite populations after the application of ACARISIN™, with visible effects within the first 24-48 hours and protection persistence for 3-6 months under adequate storage conditions.
Shelf Life
Products treated with ACARISIN™ show an average increase of 40% in their shelf life compared to untreated products or those treated with conventional methods, while maintaining their organoleptic characteristics intact for longer periods.
Economic Performance
Cost-benefit analyses conducted in food sector companies demonstrate an average return on investment of 1:5, with significant savings derived from the reduction of spoilage losses, batch rejections, and costs associated with corrective treatments.
Prevention
The preventive application of ACARISIN™ has proven to be up to 95% effective in preventing new infestations, even in environments with high risk or a previous history of recurrent problems with mites and insects in stored products.
These results have been validated in both controlled laboratory trials and real-world applications across various food industries, confirming the effectiveness of ACARISIN™ and ECO-EFF™ under varied usage conditions. The data consistently show significant superiority over conventional methods, especially in terms of persistence of the protective effect and absence of negative impact on product quality.
Competitive Advantages of ACARISIN™ / ECO-EFF™
Integrated Solution
Unlike other products that address partial aspects of the problem, ACARISIN™ and ECO-EFF™ offer:
  • Combined acaricidal, insecticidal, and fungicidal action in a single product
  • Both curative (elimination) and preventive (continuous protection) effect
  • Applicability at various stages of the food chain
  • Compatibility with different types of food and raw materials
This versatility reduces the need for multiple treatments and simplifies protection protocols.
Certified Safety
The safety profile of these products represents a fundamental competitive advantage:
  • Unique in its category with authorization for direct use in food
  • No waiting periods or need for post-treatment removal (except for surface treatment on ham)
  • Total absence of toxic residues in treated products
  • Compatible with organic and sustainability certifications
  • Compliance with the strictest international regulations
This safety allows for its integration even in the most regulated industries.
Economic Profitability
The economic analysis demonstrates significant medium and long-term advantages:
  • Drastic reduction of losses due to spoilage and contamination
  • Decrease in rejections during quality controls
  • Extension of the shelf life of high-value products
  • Less need for inventory rotation
  • Protection of brand reputation and customer loyalty
The initial investment is quickly recouped through reduced losses and increased perceived quality.
Ease of Implementation
Integration into existing industrial processes is simple and efficient:
  • Multiple formats adapted to different needs (liquid, powder, nebulization)
  • Does not require specialized equipment for application
  • Easy incorporation into existing HACCP protocols
  • Compatible with other food safety and control measures
  • Specialized technical support to optimize its implementation
This flexibility facilitates its adoption by companies of any size.
Sustainability: Environmental and Social Impact
Contribution to Green Chemistry
ACARISIN™ and ECO-EFF™ are perfect examples of the application of green chemistry principles in the food industry:
Elimination of Toxins
They completely replace traditional chemical acaricides and insecticides, reducing the exposure of workers, consumers, and ecosystems to potentially harmful compounds. This reduction of the chemical load in the food chain has a cumulative positive impact on public health.
Total Biodegradability
Unlike many synthetic compounds that persist in the environment for years, ACARISIN™ and ECO-EFF™ naturally break down into harmless substances, leaving no toxic residues or contributing to soil and water contamination. This closed life cycle represents a significant advance in sustainability.
Energy Efficiency
The production processes for these products require significantly less energy than the synthesis of traditional chemical compounds, reducing the carbon footprint associated with food protection. Furthermore, their effectiveness at ambient temperature eliminates the need for refrigeration in many cases.
Positive Social Impact
The implementation of these biotechnology solutions generates tangible social benefits:
  • Improved global food safety by reducing pre- and post-harvest losses
  • Protection of the health of food sector workers
  • Reduction of chemical residues in food consumed by the population
  • Contribution to the sustainability of agricultural communities
  • Support for corporate social responsibility policies
These products align perfectly with the UN, EU, and other governmental regulators' Sustainable Development Goals, especially those related to health, responsible consumption, and climate action.
Compliance and Regulation
Safety Assessments
ACARISIN™ and ECO-EFF™ have undergone rigorous toxicological and ecotoxicological evaluation processes following international standards:
  • Acute and chronic toxicity studies
  • Genotoxicity and carcinogenicity assessments
  • Analysis of potential effects on non-target organisms
  • Biodegradability and environmental persistence studies
  • Residue evaluation in treated products
All studies have been conducted by independent accredited laboratories, ensuring the objectivity and reliability of the results. (See SDS/MSDS)
European Regulatory Framework
The products comply with strict European regulations applicable to products in contact with food:
  • Regulation (EC) No 1133/2008 concerning food additives
  • Regulation (EU) No 528/2012 concerning biocidal products (exclusion from registration requirement)
  • Regulation (EC) No 1935/2004 on materials and articles intended to come into contact with food
  • Regulation (EC) No 834/2007 on organic production
  • Authorized for use in the manufacturing of animal feed and food products for animals.
This conformity allows their use throughout the European Union without significant restrictions.
International Certifications
In addition to basic regulatory compliance, the products have obtained additional certifications that endorse their quality and safety:
  • Possible use in organic farming (due to their composition)
  • Recognition as a low-risk substance according to FAO criteria
  • Conformity with GFSI (Global Food Safety Initiative) standards
  • Approval for use in IFS and BRC certified facilities
  • Compatible with HACCP systems and other food safety management regulations
These certifications facilitate their adoption by companies committed to the highest quality standards.
The rigorous regulatory compliance of ACARISIN™ and ECO-EFF™ provides user companies with the peace of mind of using completely legal and safe products, minimizing regulatory and reputational risks associated with pest control in the food industry.
Authorized Uses of ACARISIN™ and ECO-EFF™
USE AS A PROCESSING AID
This product is a technological processing aid in its primary assigned functions. As a technological processing aid, it is excluded from Regulation EC 1333/2008 and related legislation.
USE IN HUMAN FOOD
This product is suitable for human consumption as an additive or preparation based on additives (2) as defined in Regulation CEE112390/2011 and primarily as a leavening agent in food applications. It complies with USP monograph specifications for sodium bicarbonate and FCC standards.
For permitted uses according to Reg. EC 1333/2008 and related legislation.
USE IN ANIMAL FEED
This product is considered a Compound Complementary Feed, in accordance with current European regulations (Catalogue of Basic Raw Materials) Reg. EC 68/2013 and Reg. EU 2017/1017, as well as Reg. EC 185/2005 and Reg. EC 183/2003 on feed additives.
USE AS A PHYTOSANITARY PRODUCT
This product can be used as a phytosanitary product without prior authorization, in accordance with Art. 28 and related articles of Regulation 1107/2009.
USE IN PEST CONTROL
This product can be used for pest control functions, or as an agent for controlling certain microorganisms, including fungi and bacteria. Exempt from Biocidal Product Registration in accordance with Art. 2, Paragraph 2, subparagraph f) of Reg. EU 528/2012 in relation to Art. 2, Point 2, subparagraph a) of Regulation 1333/2008.
Success Stories and Testimonials
Cereal Industry
"After implementing ACARISIN™ in our storage silos, we have reduced mite infestations by 95% in just three months. Losses due to deterioration have drastically decreased, and the quality of our grain remains stable for much longer periods."
— Quality Director, Colombian Cereal Cooperative
Implementation in this cooperative resulted in:
  • 95% reduction in mite population
  • 78% decrease in spoilage losses
  • 1:7 ROI in the first year of use
Aged Cheese Producers
"As artisanal producers of aged cheeses, we always sought a solution that respected the natural maturation process without introducing chemicals. ACARISIN™ has been the perfect answer: it protects our cheeses from mites without altering the flavor or quality at all. Furthermore, it has allowed us to maintain our organic certification."
— Master Cheesemaker, Reggio-Emilia Roma Artisanal Cheesery
Results in the cured products industry:
  • Complete elimination of infestations in ripening chambers
  • 85% reduction in quality rejections
  • Extension of shelf life for high-end products
  • Maintenance of organic certifications and designations of origin

Proven Satisfaction: Surveys conducted among industrial users show a 98% satisfaction rate and a reorder rate of over 95%, confirming the effectiveness and acceptance of these solutions in real production environments.
Conclusion and Call to Action
The Future of Food Protection Against Infestations is Here
ACARISIN™ and ECO-EFF™ represent a paradigm shift in how we protect our food, offering a real, effective, and sustainable alternative to traditional methods based on toxic chemicals.
This biotechnological revolution allows for:
Superior Protection
Demonstrated efficacy against mites, insects, and fungi that surpasses conventional methods, with visible and lasting results that significantly improve food quality and safety.
Real Sustainability
A genuine commitment to environmental protection and public health, eliminating the need for toxic compounds in the food chain and contributing to a cleaner and safer future.
Proven Profitability
An economically viable solution that not only reduces direct losses but also adds value to protected products, improving their positioning in markets increasingly demanding quality and sustainability.
How to Implement These Solutions?
INTABIOTECH offers a comprehensive service to ensure successful implementation:
  1. Personalized Diagnosis: Evaluation of your specific needs and critical points
  1. Implementation Plan: Design of a protocol adapted to your production reality
  1. Training: Staff training for optimal application
  1. Follow-up: Monitoring of results and necessary adjustments
  1. Continuous Support: Permanent technical advice
Contact INTABIOTECH today
or ask us about Authorized Distributors in your country or region.
Discover how ACARISIN™ and ECO-EFF™ can transform the protection of your food products
www.intabiotech.com | [email protected] | +34 881 092 720
www.acarisin.info